August 30, 2016 – Ribosomal Protein (RP) genes are co-regulated in the genome, under the control of multiple regulators: Rap1, Fhl1, Ifh1, Sfp1, and Hmo1. A majority of RP genes contain a Rap1 motif upstream of the TSS. It has been shown that Rap1 acts as a master regulator, recruiting other TFs to mediate RPG regulation….
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Eberly Office for Innovation aids tech transfer partnerships Tara Immel June 10, 2016 Across the University, researchers are continually making discoveries and creating inventions that can have real-world impact and societal benefits. Although this intellectual property (IP) and innovation often can result in improving health, developing new materials, and addressing environmental issues, among other important…
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Discovered: How to unlock inaccessible genes 29 January 2016 It was known that the DNA in cells is wrapped around proteins in structures called nucleosomes that resemble beads on a string, which allow the genetic material to be folded and compacted into a structure called chromatin. “We knew that the compaction into chromatin makes genes…
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Seven Penn State Researchers named AAAS Fellows By A’ndrea Elyse Messer November 30, 2015 UNIVERSITY PARK, Pa. — Seven Penn State faculty members have been named Fellows of the American Association for the Advancement of Science, the organization announced November 23, 2015. The 2015 Fellows are Leonard S. Jefferson, Evan Pugh University Professor in Physiology;…
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New approach discovered for brain repair Chemical transformation of human glial cells into neurons Barbara K. Kennedy October 26, 2015 UNIVERSITY PARK, Pa. — For the first time, researchers have used a cocktail of small molecules to transform human brain cells, called astroglial cells, into functioning neurons for brain repair. Their results provide proof-of-principle that…
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2015 CEGR Fall Retreat Every year, the PIs leading the labs in The Center for Eukaryotic Gene Regulation (CEGR) invite their staff and families to a Fall retreat. Our faculty host a Center-wide activity outside of normal collaborative lab work and the Megameeting on Tuesdays. This year’s event will be hosted at Shaver’s Creek on Friday, October 16th…
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Song Tan awarded Faculty Scholar Medal for Outstanding Achievement June 18, 2015 UNIVERSITY PARK, Pa. — Song Tan, professor of biochemistry and molecular biology at Penn State, has been selected to receive the 2015 Penn State Faculty Scholar Medal for Outstanding Achievement in the Life and Health Sciences. Established in 1980, the award recognizes scholarly…
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Disabling infection-fighting immune response speeds up wound healing in diabetes Sam Sholtis June 15, 2015 UNIVERSITY PARK, Pa. — One of the body’s tools for fighting off infection in a wound may actually slow down the healing process, according to new research by a team of Harvard University, Boston Children’s Hospital, and Penn State University…
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McGinty honored with Dale F. Frey Award for Breakthrough Scientists March 23, 2015 Robert McGinty, a Damon Runyon Postdoctoral Fellow, in the laboratory of Penn State Professor of Biochemistry and Molecular Biology Song Tan, has been presented with the Damon Runyon Dale F. Frey Award for Breakthrough Scientists. McGinty is the first Penn State scientist…
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Structural biology: Enzyme–chromatin complex visualized Jürg Müller & Christoph W. Müller Affiliations Corresponding authors Nature 514, 572–573 (30 October 2014). doi:10.1038/514572a Published online 29 October 2014 Article tools PDF Citation Rights & permissions Article metrics The structure of an enzyme that is bound to a nucleosome — a protein complex around which DNA is wrapped —…
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