August 30, 2016 – Ribosomal Protein (RP) genes are co-regulated in the genome, under the control of multiple regulators: Rap1, Fhl1, Ifh1, Sfp1, and Hmo1. A majority of RP genes contain a Rap1 motif upstream of the TSS. It has been shown that Rap1 acts as a master regulator, recruiting other TFs to mediate RPG regulation….
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Discovered: How to unlock inaccessible genes 29 January 2016 It was known that the DNA in cells is wrapped around proteins in structures called nucleosomes that resemble beads on a string, which allow the genetic material to be folded and compacted into a structure called chromatin. “We knew that the compaction into chromatin makes genes…
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Frank Pugh Honored as an Evan Pugh Professor at Penn State 09 May 2014 B. Franklin Pugh, Willaman Professor in Molecular Biology and professor of biochemistry and molecular biology at Penn State University, has been honored by the University with the title of Evan Pugh Professor. The title is the highest honor that Penn State…
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Packaging Process for Genes Discovered in New Research 19 May 2011 Scientists at Penn State University have achieved a major milestone in the attempt to assemble, in a test tube, entire chromosomes from their component parts. The achievement reveals the process a cell uses to package the basic building blocks of an organism’s entire genetic…
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