Timothy Kunz honored as the recipient of the 2017 Fred Wedler Outstanding Undergraduate Dissertation Award

Timothy Kunz honored as the recipient of the 2017 Fred Wedler Outstanding Undergraduate Dissertation Award July 10, 2017 – Timothy Kunz, a recent graduate of Penn State’s Biochemistry and Molecular Biology Program, was honored as the recipient of the 2017 Fred Wedler Outstanding Undergraduate Dissertation Award.  Kunz received notification on April 26, 2017. Each year,…

Read More

Climbing the ladder

Climbing the ladder Schreyer Scholars gain valuable lab experience while helping to develop new DNA plasmids Jeff Rice May 31, 2017 UNIVERSITY PARK, Pa. — Turner Pecen didn’t have a lot of lab experience when he came to Penn State as a freshman in 2013. The project he spent much of his college career working…

Read More

Penn State DNA ladders: inexpensive molecular rulers for DNA research

Penn State DNA ladders: inexpensive molecular rulers for DNA research Sam Sholtis May 26, 2017 UNIVERSITY PARK, Pa. — New, license-free DNA ladders will allow researchers to estimate the size of fragments of DNA for a fraction of the cost of currently available methods. A research team of undergraduate students led by Penn State Professor…

Read More

Invent Penn State’s Fund For Innovation helps start seven new ventures

Invent Penn State’s Fund For Innovation helps start seven new ventures April 12, 2017 UNIVERSITY PARK, Pa. — A little less than two years after the launch of the Fund for Innovation, Invent Penn State has backed nearly 50 emerging Penn State technologies and has provided startup funding to promising new ventures that were born…

Read More

DR. ROSS HARDISON – “VALIDATED SYSTEMATIC INTEGRATION OF EPIGENOMIC DATA: A VISION FOR EPIGENOMICS IN HEMATOPIETIC GENE REGULATION”

April 8, 2017 – A guiding principle of developmental biology is the fact that differential gene expression determines the distinctive properties of each cell type. Lineage-specific transcription factors are required for these cell lineages. In the case of hematopoiesis, the GATA1-ES cells contribute to many cell types and organs but not erythroid cells — lineage-restricted transcription factors…

Read More

Grant to help pave a big data highway to explore genome, enhance health

Grant to help pave a big data highway to explore genome, enhance health By Matt Swayne February 14, 2017 UNIVERSITY PARK, Pa. — A $6.1 million, five-year grant from the National Institute of Diabetes, Digestive and Kidney Diseases at the National Institutes of Health may help researchers leverage massive amounts of genomic data to develop…

Read More

How to Make a Motor Neuron

How to make a motor neuron Mechanisms underlying direct programming of stem cells could eventually lead to cell-replacement therapies Sam Sholtis December 8, 2016 UNIVERSITY PARK, Pa. — A team of scientists has uncovered details of the cellular mechanisms that control the direct programming of stem cells into motor neurons. The scientists analyzed changes that…

Read More

BG STUDENT SEMINARS: LILA REIBER

November 28, 2016 – Lila is a third year graduate student in Dr. Shaun Mahony’s lab. This week she presented her work aimed at 3-D genome reconstruction from kilo base-pair resolution Hi-C data. The knowledge of a three-dimensional chromatin structure is important for studying many biological processes at the molecular level such as transcription regulation,…

Read More

2016 CEGR Fall Retreat

2016 CEGR Fall Retreat Every year, the PIs leading the labs in The Center for Eukaryotic Gene Regulation (CEGR) invite their staff and families to a Fall retreat. Our faculty host a Center-wide activity outside of normal collaborative lab work and the Megameeting on Tuesdays.  This year’s event will be hosted at the Civil Engineering Lodge on Lake…

Read More

CHIP-EXO REVEALS THE PRINCIPLES OF RP GENE CO-REGULATION

August 30, 2016 – Ribosomal Protein (RP) genes are co-regulated in the genome, under the control of multiple regulators: Rap1, Fhl1, Ifh1, Sfp1, and Hmo1. A majority of RP genes contain a Rap1 motif upstream of the TSS. It has been shown that Rap1 acts as a master regulator, recruiting other TFs to mediate RPG regulation….

Read More